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br Materials and methods br Results br Discussion To
2019-05-08
Materials and methods Results Discussion To our best knowledge, a multi-modality approach to systematically characterize an OS in vivo orthotopic model, using an aggressive OS cell line has not been previously reported. The advantage of using multi-modality approach i.e. BLI, histopathology
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Introduction Osteosarcoma OS is the most commonly
2019-05-08
Introduction Osteosarcoma (OS) is the most commonly diagnosed histological form of primary bone tumor with high morbidity, and it is mainly prevalent in teenagers and young people [1]. Pain is the most common early symptom of OS and can cause fracture of the affected bone. Currently, multiple thera
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The greater relative importance of
2019-05-07
The greater relative importance of indirect causes could be a result of successful addressing of direct complications of pregnancy and childbirth, and of a change in risk factors and disease patterns. Indirect causes of death include the effects of pre-existing disorders, such as HIV infection, ment
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Respecto a la ideolog a que
2019-05-07
Respecto gamma secretase inhibitor la ideología que ostentó en los años ochenta, temporalidad en que fue ajusticiado el coronel Máximo Zepeda, podemos decir que ésta se fue matizando durante su larga trayectoria periodística hasta su decadencia financiera y posterior desaparición, la que fue examina
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retinoid x receptor Findings children from households were e
2019-05-07
Findings 5254 children from 3376 households were enrolled either at baseline or during the trial period. Mean 20-h kitchen concentration of PM2.5was reduced from 1386 μg/m3 to 930 μg/m3 There was a strong secular decline in the incidence of ALRI over the period of the study. The intervention was ass
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br Ablation strategies from targeted to homogenization The
2019-05-07
Ablation strategies – from targeted to homogenization The techniques and principles originally developed in postinfarction scar have been translated and applied to patients with various etiologies of fibrosis and confluent scar including Chagasic cardiomyopathy, nonischemic cardiomyopathy, arrhyt
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br Algorithm of treatment approach in Brugada syndrome patie
2019-05-07
Algorithm of treatment approach in Brugada syndrome patients with electrical storm Fig. 4 shows the flow diagram of how we treat BrS patients with ES. Patients are admitted to the ICU and should be well sedated, and some may require general anesthesia with endotracheal intubation. The patients ar
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AVE 0991 br Purpose br Methods Participating centers Forty m
2019-05-07
Purpose Methods Participating centers: Forty main ICSD centers in Japan from Hokkaido to Okinawa, which cover approximately 20% of all new ICSD patients in Japan, are participating in the present study. After obtaining written informed consent, all patients (over 20 years old) will be register
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Primary lymphoma of bone is an uncommon
2019-05-07
Primary lymphoma of bone is an uncommon clinical entity and accounts for less than 5% of malignant bone tumors, 4–5% of extra nodal lymphoma and less than 1% of all non-Hodgkin\'s lymphoma. Diffuse large-B-cell lymphoma (DLBCL) accounts for the majority of cases of PBL [2]. The varied clinical and h
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br Introduction Once metastatic breast cancer cells are
2019-05-07
Introduction Once metastatic breast cancer 5-aminosalicylic acid are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and deg
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We established Wt and two
2019-05-07
We established Wt- and two Mt- (p.R308P and p.A350_N351ins8)-GATA2-expressing 32D sglt-2 to analyze the cellular effects of Mt-GATA2 (Fig. 3A). Immunofluorescence analysis revealed that Mt-GATA2 showed similar localization in the nucleus as Wt-GATA2 (Fig. 3B). Both Wt- and mutant-GATA2-expressing 3
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There are a number of reasons for this
2019-05-07
There are a number of reasons for this disparity: people with disabilities are disproportionately poor, lacking in access to education and employment, and excluded from social networks. Health-care facilities, equipment, and transportation are often inaccessible. But another significant factor is th
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Among patients with established infection in
2019-05-07
Among patients with established infection in the bone or surrounding tissue (Stage II) antibiotic penicillin-based therapy in addition to mouthwash may result in healing in patients with minor ONJ lesions. However, a large proportion of cases tend to show chronically infected necrotic process in jaw
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Por otro lado cabe subrayar que esta eleg a
2019-05-07
Por otro lado, cabe subrayar que esta “elegía” de Pellicer se asemeja al género precolombino del icnocuicatl, los “Canto[s] de desolación, de orfandad” (Garibay 1992: 89). Según Garibay, estos cantos precolombinos “tienen parentesco con las elegías […] de los poetas de Occidente, en que se canta la
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Complete surgical resection of the
2019-05-06
Complete surgical resection of the tumor at the time of diagnosis is essential towards effective management of PPB. Unfortunately, a large cohort of patients present with an advance stage of disease where the tumor has grown to such an extent to invade surrounding vital structures, hindering the com
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