• br Introduction Patients with advanced breast prostate

  2019-05-08

  

  Introduction Patients with advanced breast, prostate, lung and colo-rectal cancer frequently develop bone metastases (BMs). These lesions may be asymptomatic or may cause pain, pathologic fractures, malignant hypercalcemia, epidural spinal cord compression and/or shorten survival [1]. The underly

• Importa acentuar que la colonialidad no descansa sobre la ec

  2019-05-08

  

  Importa acentuar que la colonialidad no descansa sobre la economía como tal, y menos sobre la literatura, sino sobre el devenir de la episteme racial gestada durante el legado colonial latinoamericano. Con ello busca no sólo, o no tanto, una relectura de la historia latinoamericana sino más bien una

• Para garantizar la aplicaci n y permanencia de las reformas

  2019-05-08

  

  Para garantizar la aplicación y permanencia de las reformas emprendidas, se necesitaba de un marco normativo institucional que brindara estabilidad al modelo, emitiendo señales de confianza al capital transnacional y otros actores privados que invertían en Perú. La Constitución de 1993, elaborada po

• With centralisation timely and efficient distribution networ

  2019-05-08

  

  With centralisation, timely and efficient distribution networks are key. However, mature blood distribution networks are yet to be established in most developing countries. For example, blood donated in Malawi\'s capital Lilongwe is sent to Blantyre (360 km away) for testing at MBTS before it is tra

• br Materials and methods br Results br Discussion To

  2019-05-08

  

  Materials and methods Results Discussion To our best knowledge, a multi-modality approach to systematically characterize an OS in vivo orthotopic model, using an aggressive OS cell line has not been previously reported. The advantage of using multi-modality approach i.e. BLI, histopathology

• Introduction Osteosarcoma OS is the most commonly

  2019-05-08

  

  Introduction Osteosarcoma (OS) is the most commonly diagnosed histological form of primary bone tumor with high morbidity, and it is mainly prevalent in teenagers and young people [1]. Pain is the most common early symptom of OS and can cause fracture of the affected bone. Currently, multiple thera

• The greater relative importance of

  2019-05-07

  

  The greater relative importance of indirect causes could be a result of successful addressing of direct complications of pregnancy and childbirth, and of a change in risk factors and disease patterns. Indirect causes of death include the effects of pre-existing disorders, such as HIV infection, ment

• Respecto a la ideolog a que

  2019-05-07

  

  Respecto gamma secretase inhibitor la ideología que ostentó en los años ochenta, temporalidad en que fue ajusticiado el coronel Máximo Zepeda, podemos decir que ésta se fue matizando durante su larga trayectoria periodística hasta su decadencia financiera y posterior desaparición, la que fue examina

• retinoid x receptor Findings children from households were e

  2019-05-07

  

  Findings 5254 children from 3376 households were enrolled either at baseline or during the trial period. Mean 20-h kitchen concentration of PM2.5was reduced from 1386 μg/m3 to 930 μg/m3 There was a strong secular decline in the incidence of ALRI over the period of the study. The intervention was ass

• br Ablation strategies from targeted to homogenization The

  2019-05-07

  

  Ablation strategies – from targeted to homogenization The techniques and principles originally developed in postinfarction scar have been translated and applied to patients with various etiologies of fibrosis and confluent scar including Chagasic cardiomyopathy, nonischemic cardiomyopathy, arrhyt

• br Algorithm of treatment approach in Brugada syndrome patie

  2019-05-07

  

  Algorithm of treatment approach in Brugada syndrome patients with electrical storm Fig. 4 shows the flow diagram of how we treat BrS patients with ES. Patients are admitted to the ICU and should be well sedated, and some may require general anesthesia with endotracheal intubation. The patients ar

• AVE 0991 br Purpose br Methods Participating centers Forty m

  2019-05-07

  

  Purpose Methods Participating centers: Forty main ICSD centers in Japan from Hokkaido to Okinawa, which cover approximately 20% of all new ICSD patients in Japan, are participating in the present study. After obtaining written informed consent, all patients (over 20 years old) will be register

• Primary lymphoma of bone is an uncommon

  2019-05-07

  

  Primary lymphoma of bone is an uncommon clinical entity and accounts for less than 5% of malignant bone tumors, 4–5% of extra nodal lymphoma and less than 1% of all non-Hodgkin\'s lymphoma. Diffuse large-B-cell lymphoma (DLBCL) accounts for the majority of cases of PBL [2]. The varied clinical and h

• br Introduction Once metastatic breast cancer cells are

  2019-05-07

  

  Introduction Once metastatic breast cancer 5-aminosalicylic acid are in the bone marrow, they hijack signals coming from the normal bone remodelling process and promote bone degradation [1]. Bone degradation is caused by osteoclasts, which have the unique property to dissolve bone mineral and deg

• We established Wt and two

  2019-05-07

  

  We established Wt- and two Mt- (p.R308P and p.A350_N351ins8)-GATA2-expressing 32D sglt-2 to analyze the cellular effects of Mt-GATA2 (Fig. 3A). Immunofluorescence analysis revealed that Mt-GATA2 showed similar localization in the nucleus as Wt-GATA2 (Fig. 3B). Both Wt- and mutant-GATA2-expressing 3

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